Electrochemical activities of some heterocyclic compounds containing benzimidazole moiety

Abstract

A number of N-substituted benzimidazole derivatives have been synthesized and tested for their antibacterial
activities. The chemical structures of the newly synthesized compounds were verified on the basis of spectral and
elemental methods of analysis. Apart of this electrochemical analysis are performed on these derivatives. The
electrochemical reduction of these compounds takes place in a single, two-electron transfer, diffusion- controlled,
irreversible wave in the pH range 2.0-12.0 at dropping mercury and glassy carbon electrodes. A plausible reduction
mechanism is suggested on the basis of cyclic voltammetric, polarographic and coulometric studies. Kinetic parameters,
i.e., charge transfer coefficient (n) and forward rate constant (K
0
f, h) have also been calculated. In this paper we present
new data on the electrochemical activities of 4,6-diphenyl-5[2-(2-methylprop-1-enyl)-1H benzimidazole-1yl] pyrimidene2-(5H)-thione derivatives.